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CoolSculpting ®

CoolSculpting® is a cryolysis, or fat freezing device, and concept trademarked by Zeltiq Aesthetics Ltd.

The clinical science, which led to the of their cryolipolysis and the CoolSculpting device, was first in 2008. Dieter MD, PhD and R. Rox Anderson and their team demonstrated that under conditions, fat cells the skin and muscle layers, (i.e. subcutaneous fat), is more to the of cold than other surrounding tissues. They also showed that prolonged cooling of these fat cells can cause them to reduce in number, anything else in the area.

This was referred to as `selective cryolysis`. Where `cryo` refers to cold and `lysis` refers to the disruption of a cell wall which leads to its disintegration.

Zeltiq began marketing this as cryolipolysis or cryolipo. It is now part of the portfolio of treatments from Allergan Aesthetics, the makers of Botox® and .

The CoolSculpting device uses a variety of applicator heads for tissue-cooling, down to −7°C, and is precisely controlled by an monitoring system.

By the applicator to the area, the tissue is drawn into the cup-like shape under vacuum and held in place two cooling panels. Then, energy, in the form of heat, is from the area and the fatty tissue is cooled.

Sensors in the applicator heads monitor the skin during the to ensure a and consistent . Cooling can be adjusted throughout thanks to this continuous feedback from the device comes with a variety of applicators for different areas of and some clinics may have more at their than others.

• CoolMini™ Applicator is ideal for small areas of fat, including double chin
• CoolCurve+™ Applicator is ideal for curves, such as the flank area (love or muffin tops).
• CoolCore™ Applicator is most used for the abdomen.
• CoolAdvantage Petite™ is to treat upper arms.
• CoolAdvantage™ Applicator is a newer with interchangeable contours and is ideal for the abdomen, flanks and inner thighs and claims to treat in nearly half the treatment time of previous models.
• CoolFit™ a flat applicator design ideal for longer, vertical areas of fat, such as the inner thighs.
• PRO™ Applicator features a unique flat applicator design ideal for non-pinchable fat, such as outer thighs.

• CoolMax™ Applicator is ideal for large volume .

Cryolipolysis using the CoolSculpting device, is a fat removal procedure. It is the of the subcutaneous fat cells, which induces lipolysis, the breaking down of the fat cells by crystallising them, without any of the tissue or the skin. Following the procedure, the fat breaks down over a period of two to four months, resulting in fat loss that entirely natural.

During treatment, a gel pad is to skin and the applicator head is and . This draws in the tissue in the area being targeted using vacuum, and the controlled can then be .

European CE Mark approved in 2009.

U.S. FDA (Food & Drug Administration) in September 2010 for the non-surgical of fat for the flank area (or love handles), May 2012 for the non-surgical of fat for the abdomen area (belly fat), April 2014 to treat the thigh area, September 2015 for submental fat (double chins), April 2016 for the of fat bulges of bra fat, back fat and underneath the buttocks (also known as banana roll) and January 2017 for of the upper arms.

Trained medical professionals, including and nurses, as well as trained advanced aestheticians.

Cryolipolysis is used to reduce fat in specific areas of the body where there is `pinchable` deposits of fatty tissue, such as on the abdomen, back, thighs, hips, legs, arms and chin.

Ideal candidates have small, areas of fat and are generally fit and healthy. Common areas to treat include love handles, bra bulges, saddle bags, bingo wings, or muffins tops that are not easily reduced through diet and . As well as post where small accumulations of fatty tissue have remained.

It is not intended as a weight loss solution, and it is not suitable for treating large areas of fat, where liposuction may be more appropriate. It is for all skin types and can be used to treat both men and women.

Results from treatment will begin to show approximately 3 weeks after treatment, with more dramatic results after 2 months. The of the fat cells will continue for up to 4 or 6 months after treatment, so expect to see your final results after around half a year.

The fat cells do not regrow or return, therefore the treatment is considered permanent. a healthy diet and is important to avoid weight gain in the fat cells.

is generally well . You will feel an cold as the treatment begins but this usually subsides within 5 to 10 minutes as the area being targeted is numbed. As the draws in the tissue within the area being treated you will also feel a akin to or mild . Other possible include tingling, stinging, aching or cramping as the treatment gets underway.

Most people are happy to be doing other things during treatment, such as read, use mobile devices or even have a rest and nap as the treatment is well tolerated.

Many return to their normal straight away afterwards with little experienced. Expect to experience temporary side effects redness, bruising, swelling, tingling, to the skin, tenderness, itching and to the area. You may find your skin is to the touch. If you have treatment to reduce a double chin, then you may experience a sensation of fullness in the back of the throat. All these and side should within a few days, or up to a week after your treatment .

Although rare, cases of pain and paradoxical hyperplasia (PAH), where accumulation of more fatty tissue appears in the treated area, have been reported post . PAH is reportedly a more common occurrence in men than women, and can be successfully resolved with .

Other rare, but side include, first or second degree burns (frostbite), due to of the applicator, of the skin in the area (dark patches), or during treatment and hernia.

As long as you are generally healthy and don`t have any skin or infections in the area treated, there are few why you should not this .

and breast women are not suitable candidates.

You should also not have the if you have a known to cold, impaired tissue sensitivities, or suffer from (a type of vasculitis), cold disease (a rare blood disease), or paroxysmal cold hemoglobinuria (also known as Donath-Landsteiner syndrome). Please check with your GP if you are unsure about any health you may have.

Due to the risks associated with adipose hyperplasia, and the anatomical differences in fat between men and women, some men may not be for CoolSculpting . Current advice published by Dermatologist, Dr. Terrence Keaney et al in 2016 notes that "careful patient selection avoiding men with visceral abdominal adipose and firm, non-distensible, fibrous fat may be important to minimise the risk of paradoxical adipose hyperplasia".

 The time taken for a session will depend upon the size and number of areas being . areas can be at one visit, depending on the indication, and the available to the clinic. Newer models of the also offer shorter times. A normal session for one area should take between 30 and 60 minutes.

The number of required will depend on the area being treated, but most require between 1 and 3 sessions.

The cost of CoolSculpting treatment on the size and number of areas being treated. Most people have more than one area of their body and a treatment plan can be drawn up for this. Expect to pay between £1,500 and £3,500 for most typical treatment plans.

 (Before, left, After, right) 5 weeks after of Dr. Tracy at The Skin Clinic, Buckinghamshire.

(All before and Nasolabial Fold (Smile Line Fillers) after are real patients, your results may differ).

Cryolipolysis® reduces excess adipose tissue
Nelson AA, D, Avram MM. Cryolipolysis® for the of Excess Adipose Tissue.
Semin Cutan Med Surg.

Efficacy & safety demonstrated in studies
Avram MM, Harry RS. for Subcutaneous Fat Layer .
Lasers Surg Med.

A Study of Noninvasive for Subcutaneous Fat Layer Reduction
Dover J, Burns J, S, et al.

Selective Cryolysis: A Novel Method of Noninvasive Fat Removal.
D, H, Watanabe K, et al.
Lasers Surg Med.

for Fat Cell Destruction: Initial Results From a Pig Model.
Zelickson B, Egbert BM, J, et al.
Dermatol Surg.

for Fat Reduction Does Not Affect Serum Lipid Levels or Liver Tests.
Klein KB, Zelickson B, Ropelle JG, et al.
Lasers Surg Med.

Clinical Efficacy of Noninvasive Cryolipolysis® and Its on Peripheral Nerves.
Coleman SR, K, Egbert BM.
Plast Surg.

Safety, Tolerance, and Patient Satisfaction With Noninvasive Cryolipolysis®.
CC, Mazer JM, Sand M, et al.
Dermatol Surg.

Longitudinal Evaluation of .
Bernstein EF.
J Cosmet Dermatol.

Broad of a and With CoolSculpting.
Stevens WG, LK, Spring MA.
Aesthetic Surg J.

Industry

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All information within this site is carefully researched and for accuracy of content. Please note that for prospective purchasers of aesthetic treatments, information and provided does not an consultation with an experienced practitioner.